@stephen59
Are you getting a MRI/Ultrasound Fusion Biopsy? That is really essential in order to make sure the PIRADS 4 lesion has at least 3 cores out of it. The biopsy only gets about 1% of the prostate so they may have missed the cancer, like the doctor says.

They can get to more of the prostate with a transperineal biopsy. It is also less likely to caused an infection. Can your doctor do that?