I have had Tumid lupus since age 14yo. I am now 44yo. My daughter has SLE with a positive ANA. I have a Negative ANA. I also have all the signs of SLE and googled it and came across your post. I may have a diagnosis of SLE from my Rheumatologist I'm not exactly sure. But I am going to Birmingham to another Rheumatologist for further testing. My joints and muscles hurt me daily. I am taking Enbrel and Plaquenil 200mg twice daily. I have noticed some improvement. But in 2018 was admitted to the hospital with severe anemia and no major cause of blood loss. I had been treated for what my GI Dr. Said looked like a bad case of Crohn's disease and a duodenal ulcer which was superficial. Ive had kidney issues since my teen years also. Your case sounds so much like mine! I had been looking at benlysta online and it sounds like a good one. I do hope she will tey me on this drug also!