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Positive ExoDx urine test with negative MRI

Prostate Cancer | Last Active: Jan 25 8:28am | Replies (27)
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@jeffmarc ; i went ahead and got my biopsy. Just heard that 11 cores were negative. 1 core came back with 12% of core showing 3 + 3 Gleason 6. I have a follow up with Urologist after Christmas. The NP suggested I do research prior to the visit. Specifically to learn more about a Decipher Test and an Artera AI Test, which uses AI to look at the tissue on the biopsy in question. I'm not sure how to take this news....I guess it's not the best but could be worse?

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Replies to "@jeffmarc ; i went ahead and got my biopsy. Just heard that 11 cores were negative...."
Jeff Marchi | @jeffmarc | Dec 15, 2025

@joeelizabeth
You are a perfect case for active surveillance. It can’t hurt to get a decipher test and ArteraAI is more of the same, results can lead to more educated decisions. With such a low percentage of “cancer” in a 3+3 core you should review the doctors that feel people are over treated and would say to you, consider options other than treatment. A 3+3 is not considered cancer by some doctors.

Here are some videos from doctors that discuss who is a good candidate for active surveillance

Here is a video with Dr. Laurence Klotz, one of the experts on active surveillance. He can give you answers as to why you would or would not be a good candidate for active surveillance.


Here is a video by Dr. Epstein discussing active surveillance and more

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