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Anastrozole: Is it worth it?

Breast Cancer | Last Active: 15 hours ago | Replies (19)

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Hi! I am on my 21st month of taking Anastrozole and am wondering if anyone has had more side effects the longer you have been taking it? I am 67 years old. My hands are weak, crippled and painful. I do have arthritis but the decline in my hands is unbelievable. I also have nights where I am wide awake until 2:00 a.m. I do have a follow-up with my surgeon and oncologist next month. I had a lumpectomy followed by 5 days of radiation. Earlier after starting Anastrozole I did have hot flashes and I did / do have days of memory fog. I have also been quite moody that past few months. I am curious to know if anyone else has experienced any of these side effects or if something else might be going on besides the medication.

Thank you

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Replies to "Hi! I am on my 21st month of taking Anastrozole and am wondering if anyone has..."

@debds sorry to say but I had little to none side effects my first two years...my side effects gots very severe in yrs. 3 and 4...Oncologist stopped anastrozole after 4 years...BUT remember everyone re-acts differently to the drugs.

@debds Hi - I’ve been on Anastrozole for almost 18 months . Was ok for first couple of months then severe bone and muscle pain .I persevered for three more months then oncologist said take an 8 week break. Resumed again last September,still with some muscle effects. From Oct this year I seem to have had a surge in symptoms almost taking me back to the situation I was in when I took the respite break last year. A dispiriting experience but I have seen reference in some of the literature that it is not unheard of for some people to have this happen, just keep hoping things will level out!! Best of luck.

I started Anastrozole last month, & have had a sharp increase in arthritis pain (particularly hands & feet). It seems as though every injury I've had from childhood on has flared up, & the scarring from my mastectomy (performed 6/20) is tightening faster than I can stretch it out. The "I don't care anymore" component of estrogen loss is also apparent. I'm hoping this will diminish over time, but it sounds as though it's gotten worse for some of you.