@terryannecampbell Welcome to Mayo Clinic Connect! As you have read, there are many of us with our individual stories about fluorouracil ointment.

Please defer to your dermatologist to ask how long to do the treatment. Is there anything on the prescription label that gives you an indication? Some members here are told to do 2 weeks, or 3 weeks, some hear every other day for 4 weeks. If this is your first time using it, your doctor may have told you to watch for certain indicators, then stop.

Usually feeling a bit sore, with the redness and scabby spots, means the treatment has found areas to attack. Always a good thing!
Ginger