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Will PSA ever hit 0 or close to it?

Prostate Cancer | Last Active: Dec 18, 2025 | Replies (37)

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Profile picture for beaquilter @beaquilter

I think we all know that 0 is not exactly 0 but "undetectable" 0.1 or the like...
My question was if anyone had teetered close to it without actually hitting it.
Will my husband's PSA get low enough before it eventually goes up again (what I've read online that's worse outcome)

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Replies to "I think we all know that 0 is not exactly 0 but "undetectable" 0.1 or the..."

@beaquilter
I know a lot of people whose PSA has stuck around in the.1 to .3 or .4 Range after radiation and chemo. It doesn’t always have to hit Undetectable (< .1) To be considered the bottom for people that have those types of treatments.

The one place they expected to hit < .1 Is for people who have a prostatectomy since there is no tissue left to Produce a PSA. In those cases if it starts to rise at all, it means that the cancer has come back somewhere.

My brother is a perfect example. His PSA hit a bottom of .11 after radiation. It has risen a little since then, but not a significant amount. I know people who’ve had chemo that have had the PSA produce all different types of results, For some people, it is very successful in their PSA gets very low for others. It stays in range like my brothers or even higher, because the chemo was not 100% successful.

That’s one reason they do chemo again adding carboplatin. A neighbor of mine’s father has stage “five?” prostate cancer and is going for chemo plus carboplatin on a pretty continuous basis. It seems to keep him alive. I asked her about this stage five diagnosis and she tells me that’s what the doctor calls it, I think it’s really an advanced stage four Since technically there is no stage five.