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Is ADT ever used at reduced dosage to moderate side effects?
Prostate Cancer | Last Active: Dec 17, 2025 | Replies (24)Comment receiving replies
@jeffmarc “ You could alternate Orgovyx, But you probably would end up with your testosterone down really low no matter what.”
If the end result (low testosterone) was the same, could you reason that toxicity might be reduced?
Has anyone ever just taken the pill every second day? I presume some people have but haven’t heard any reporting on it.
Replies to "@jeffmarc “ You could alternate Orgovyx, But you probably would end up with your testosterone down..."
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@ozelli
I’ve never heard of anyone trying to do that. The half-life of Orgovyx Is only 25 hours so it would leave the system quickly, but it would suppress the testosterone every time it was taken, and that would just be cumulative. It would probably take longer for the testosterone to get down, but it would do the same thing over time I suspect.
If someone doesn’t want to mess with their testosterone, lutamides can work with it. I know quite a few people on Darolutamide alone and it keeps their PSA down.