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Anyone with a PSA in the 11's or close?
Prostate Cancer | Last Active: Dec 16 9:50am | Replies (28)Comment receiving replies
@drewlevine I looked again at my biopsy final diagnosis (tissues collected on 24 Jan 2025). I wanted to give you a more accurate answer, better than just saying I trusted my urologist and radiation oncologist's diagnosis of unfavorable intermediate. Although I didn't do this level of analysis (underlining in red in the attached jpeg) prior to your question, I now fully agree, without a doubt, that I was unfavorable, due to: (a) More than half (8/14) of the sample tissues were malignant, and (b) the percentages were all high. I believe that either of these two (a or b, alone) was enough to make me unfavorable. I wasn't happy with the doctors' assessment, and I wanted to argue so that I could avoid ADT, but I decided that they knew better than I did.
How many tissue samples were there in your biopsy? How many cores were positive for malignancy?
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@vircet Thanks Vir. My second biopsy was performed after an MRI showed two new lesions of concern. The area targeted was the right prostate with 10 samples of which 7 were positive for cancer and 5 of the seven had significantly high percentages of cancer (right anterior). PSMA scan I had 6 months later showed that the cancer was still concentrated in that right anterior section with none being noted on the left side. Still my PSA is above 10 and I have 3+4 grade so that alone probably puts me in the unfavourable category which does indicate ADT. I've decided not to use ADT for now although was advised to do so by the oncology team. I've gone the radiation alone route and have one more treatment left. I did think about it a lot and realise there maybe more risk this way in terms of cancer but am mostly comfortable with my decision.