Anyone with a PSA in the 11's or close?

If your GP said "get your affairs in order" I would make getting a new GP the first step in that process. The rest can wait. 11 is elevated but as others have said, it means time to look closer. My GP started looking closer with PSA of 5.41 (previous year was 4.96 IIRC) and it progresses to a biopsy where we found very early stage cancer just above threshold for active surveillance in my urologist's opinion and in the second opinion of an unaffiliated urologist in a different metro area.. There are numerous steps and it's not an identical template for all patients.

Your story sounds a tiny bit similar to mine. At 54 (I'm 55 now), I had a PSA of 8.0 and 2 months later, 11.8. I had an MRI that showed nothing and a TRUS biopsy that showed nothing. I started on Finasteride, and 6 months later, PSA was down to 4.9. One thing about my prostate is that it was close to 200 in volume, so an enormous gland. I have essentially no side effects from any of it. All of my related "scores" seemed within a range that two Urologists weren't terribly alarmed after the MRI and TRUS. I pee normally, normal sexual function (though ejaculate volume and consistency decreased/changed after the TRUS), I only get up to pee at night if I drink too much water right before bed - and then only once, etc. I'll be back in March for the 12-month look. It will be interesting to see how things are shaping up then and the next recommended steps. I have a couple of other health issues (mini-stroke 2 years ago, high BP, Afib 2-3 times the last few years), so I can empathize with thinking through the "getting affairs in order" aspect of it all. I'm hoping that diet, exercise, weight management, mindfulness, and working with my care teams will help me stick around a good long while. I know my amazing wife is hoping I do! I'm 6'7" and weigh 335 (down from 365), and working to get to 275 (recommended weight for my wide frame - most people guess I'm 270 now as I "carry it well"). God knows what I need, and I know He will carry me no matter what happens.

Best wishes for your own journey!

@hoops0200 Thank you (and everyone else) for sharing their perspectives - much appreciated. I wonder if in your case your prostate was so large because you are a bigger guy?

@thig350 said: "I wonder if in your case your prostate was so large because you are a bigger guy?"

I have heard that, and my Urologist said it could have something to do with it. He didn't seem to want to offer an informed opinion on it, though. But, yes, being this tall and having some size was great in the younger days, especially! But now? It's just hard to find clothes that fit well!

Just want to add my recommendation that you take a PSE test as soon as you can. This is a newer technology genomic test that is considered more accurate and a better indicator of the presence of prostate cancer than the PSA test. Tests based on this technology are identifying presence of cancer in men that otherwise would not be suspected of having cancer (I am one of those men - I had a stable PSA and normal DRE but I asked for a similar test - the ExoDx test - as a precaution and it showed an elevated risk of cancer which was confirmed with a saturation biopsy) and these tests are helping men to avoid unnecessary biopsies.

All the best to you as you move through this process of getting further information. And it you do learn that you have prostate cancer, this forum is a great source of information on treatments and what to expect going forward.

@thig350 Yes, as @rider51 said, if you do learn that you have PC, this forum is great.
I was PSA 7.9 in late 2024, 10.05 in early February 2025. Had biopsy, whole body bone scan, and CT all in Feb; Gleason 7 (3+4), unfavorable intermediate (thankfully not yet high) risk.
I had SBRT in April, six months in Orgovyx. Off ADT almost three months now. Let's hope for the best that you don't have PC yet.

I had proton radiation in 2010 and over the years, I have somewhat elevated PSA. Having completed MRI and a PET scan March 2025 with nothing evident; the consensus includes an issue with BPH. The prostate gland seems to have issues of some sort as part of the aging process. Of course, the best evidence is a biopsy. From comments on this site from many others, urologists come in different "flavors" and as such, one should obtain a second or even third opinion prior to making any definitive decision. One can surmise from reading comments that many men undertake a wide range of medications and procedures.

@westernflyer
You could get a PSE test. It’s 94% accurate in telling me whether or not you have prostate cancer in your system. If it finds you do then a biopsy should be done. If it finds you don’t, then you don’t really need one.

@vircet Do you know why @vircet your was labelled unfavourable 3+4 and not favourable? Mine has also been labelled that but don’t have a clear sense why. I have cancer in about 50-55% of right prostate and none on the left side. The cancer on right side was evaluated to be 90-94% grade 3. However, my PSA at last measurement was 15.3. I’m interested in hearing what other people know. Thanks

@drewlevine I looked again at my biopsy final diagnosis (tissues collected on 24 Jan 2025). I wanted to give you a more accurate answer, better than just saying I trusted my urologist and radiation oncologist's diagnosis of unfavorable intermediate. Although I didn't do this level of analysis (underlining in red in the attached jpeg) prior to your question, I now fully agree, without a doubt, that I was unfavorable, due to: (a) More than half (8/14) of the sample tissues were malignant, and (b) the percentages were all high. I believe that either of these two (a or b, alone) was enough to make me unfavorable. I wasn't happy with the doctors' assessment, and I wanted to argue so that I could avoid ADT, but I decided that they knew better than I did.
How many tissue samples were there in your biopsy? How many cores were positive for malignancy?