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Anyone with a PSA in the 11's or close?

Prostate Cancer | Last Active: Dec 16 9:50am | Replies (28)

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@vircet Do you know why @vircet your was labelled unfavourable 3+4 and not favourable? Mine has also been labelled that but don’t have a clear sense why. I have cancer in about 50-55% of right prostate and none on the left side. The cancer on right side was evaluated to be 90-94% grade 3. However, my PSA at last measurement was 15.3. I’m interested in hearing what other people know. Thanks

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Replies to "@vircet Do you know why @vircet your was labelled unfavourable 3+4 and not favourable? Mine has..."

@drewlevine I looked again at my biopsy final diagnosis (tissues collected on 24 Jan 2025). I wanted to give you a more accurate answer, better than just saying I trusted my urologist and radiation oncologist's diagnosis of unfavorable intermediate. Although I didn't do this level of analysis (underlining in red in the attached jpeg) prior to your question, I now fully agree, without a doubt, that I was unfavorable, due to: (a) More than half (8/14) of the sample tissues were malignant, and (b) the percentages were all high. I believe that either of these two (a or b, alone) was enough to make me unfavorable. I wasn't happy with the doctors' assessment, and I wanted to argue so that I could avoid ADT, but I decided that they knew better than I did.
How many tissue samples were there in your biopsy? How many cores were positive for malignancy?

@drewlevine
Were any of these things found in the biopsy intraductal, cribriform, Seminal vesicle invasion, EPE or ECE. (Extraprostatic extensions extra capsular extensions). They can make the cancer much more aggressive.

Your PSA is relatively high for 3+4, That could also be a factor.