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Has anyone experienced leg pain while taking Orgovyx?
Prostate Cancer | Last Active: Nov 25, 2025 | Replies (25)Comment receiving replies
@joeck
Have you considered getting gabapentin for the pain in the joints? I take 600 mg three times a day and it really does make a difference in the joint pain. I’ve tapered off of it a couple of times over the last four years and each time the pain in my joints increases So I go back to 600. I do have osteoarthritis so that doesn’t help, Had both knees and one hip replaced, and the other ones real flaky. Gabapentin seems to keep that from getting worse, though Acetaminophen helps as well.
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@jeffmarc
Funny you should mention - I just started a very low dose gaba 5 days (100mg/d). Saw my PCP this afternoon and she is 90% sure my ankle pain is an injury I didn't know I sustained. Waiting on results from xray, so maybe I won't be blaming Orgovyx for this. The neuorpathy could be my body or the ADT - we will see. We doubled the gaba dose and will keep titrating upwards to see if I can lose the PeriNeuro as I call it. Pending the results of the xray, I may need to be looking into bone deficiency remedies (as you, Jeff, and others have discussed at times).