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Weight gain: How do you control weight gain on hormone therapy (ADT)?
Prostate Cancer | Last Active: Dec 22, 2025 | Replies (50)Comment receiving replies
I agree with all that @brianjarvis said - however GLP-1 meds give two prong punch !
Yes, they slow digestion and promote satiety but the second equally important effect is stimulation of more insulin production and regulation of glucose metabolism.
Since ADT directly slows and effect glucose metabolism , GLP could give @thoffman6709 nice contra effect.
For some people who develop really slow metabolism and naturally have low muscle mass, exercise can help but not to the extent that is needed.
Gain of whooping 35 pounds in 4 months with no increase in food intake is extraordinary and points to metabolic problem. I am not a doctor, but perhaps GLP can really help in this case and GLP has other benefits beside weight loss so if it was me, I would try it.
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@surftohealth88 In recent years, they’ve opened up GPL-1 medications not just for diabetes and morbid obesity, but also for general weight loss.
Yes, as you point out the second equally important effect is stimulation of insulin production and lowering of glucose levels — and that will make him even “less hungry” (if that’s possible).
I’d be sure to ask my doctor if it was appropriate (especially if I was already “eating like a bird” due to hormone therapy).