@cookercooker it sounds like your cancer is responding well to Enhertu. Why is your doctor discussing what treatment will come after Enhertu ? My hope is that I will be cancer free for a very long time being treated with Enhertu...During my telemed conversation today, my doctor talked about decreasing the dose if I want to. She feels that I am responding so well to every 4 weeks decreasing the dose shouldn't change the efficacy of the drug. I'm going to wait until I get the results from my next PET Scan in February before making any changes. As far as what drug would come after Enhertu...who knows what will be the best available new therapy..there are new trials and research is ongoing, perhaps a drug that we know nothing about today ! Have to stay positive and grateful ...one day at a time !