Does anyone have advice on Letrozole?
I was diagnosed with ILC in July and had a lumpectomy in my right breast followed by 4 weeks of radiation. Im starting Letrozole next week. Im worried about side effects but more worried about the return of the ILC if I dont take it. Thanks for any suggestions or advice
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As our monitor/connect director Colleen Young stated, it bears repeating it helps to underline everyone is different in their response to the AIs. Of course, no one wants to take these drugs but they can save you from a re-occurrence of BC down the road. And, of course, that is not guaranteed but would you rather give it a try than not?
My personal feeling.
And, of course, women opt to not take the AIs at all for their own personal reasons. Which is to be respected.
For women who are faced with the recommended decision by their treatment team to start on an AI, take all the postings here listing side effects with a grain of salt. We all must realize that side effects that impact one...does NOT mean they will impact you in the same way. After 5 months on Anastrozole and dealing with its S/Es my breast oncologist changed me to Letrozole. And, right now, I am coping with its S/Es well. For some women, they never experience S/Es at all...for others it can be intolerable. We all know, everyone is different. So, for those recently diagnosed with BC and face this recommendation to start AIs, do not be frightened by what you read re: its side effects. Understand what happens to one woman may never happen to you! Or if you opt to take the AIs your side effects (if they present themselves) may be completely tolerable and you can cope well.
Or you might need to change to another AI if side effects are completely unbearable.
Another thought: I have found in taking my AI, I don't put lots of thinking into it. I simply take it with my morning regimen of all my medications and forget about it!
The human mind is funny...what you think about a lot, can become your reality! Don't plant such seeds in your mind. If you decide to, take it and forget about it!
The very best to you and to all! Blessings always.
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8 ReactionsSo many choices to make! I have been on Letrozole for a little over a year, and later added Verzenio, but about to switch to Ribociclib. For me, the Letrozole causes hot flashes, joint pain, and dryness. I have found acupuncture helps a lot with the first two. The dryness was worse with Verzenio in the mix (I paused that for recent reconstruction surgery), but my nails, for instance, are horrible with bending and cracking. Just started a peptide to help with that. I just recommend you start and see how it goes. Stay in communication with your oncologist to help with side effects. They have a number of tricks to help you along the way, and you can always make a change. Good luck!
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1 ReactionI took anastrozole for my first cancer and had painful thumb and hip joints which subsided after the 5years prescription. I got cancer again and took letrozole. Letrozole caused me severe dry mouth which lead to thrush and permanent damage to my salivary glands. But that doesn't mean you will have this problem too. I got severe dry mouth because I had other health issues that was not known till the letrozole brought it to the surface. If you get dry mouth just take care of it by brushing often and suck on sugarless mouth drops. CVS has mouth sprays that help too.
@claunch I take a low dosage (3mg) cannabis gummy for my insomnia. I don't take it every night just when the insomnia is more then two days in a row.
Are those available in Texas?
Good idea.
Thank you.
To MJ65: You say you are worried both about side effects of AIs and BC recurrence. My advice: there are 3 AIs + Tamoxifen (if OK in your case). If the first thing you try gives you bad side effects, then go on to the next--and so on!
In my case, I got bad tinnitus from letrozole and exemestane, but anastrozole was OK. After maybe 6 months on anastrozole, I re-tried exemestane--and had no problem. I've since read that even taking a drug holiday for a few weeks, then restarting the same med can eliminate side effects.
All this is very mysterious. While I can understand stopping AIs when every AI produces horrible side effects, I can't understand not trying. I was lucky--you may be too! In fact, from some research I read, about 30% stop AIs because of side effects. But 70% don''t! I assume that, like me, they found a way to live with their AI.