@peter800 Here is the most updated study with this issue:

Repatha (evolocumab) can sometimes cause upper-respiratory–type symptoms in a small number of people — things like runny nose, sore throat, or cold-like symptoms are listed among the more common side effects. However, it can be tricky to tell whether these symptoms are truly from the medication or just a coincidence, especially during cold/flu season.

A few points that might help:

• The timing matters. If your symptoms consistently appear right after each injection and then improve as the dose wears off, that pattern could suggest a medication-related side effect.

• “Cold symptoms” from Repatha are usually mild. True viral infections are still more likely, especially if you had bronchial congestion and symptoms lasting two weeks.

• Stopping or delaying a dose is a medical decision. Because Repatha significantly lowers LDL and reduces cardiovascular risk, it’s important to weigh potential side effects against the benefits.

What most clinicians recommend:
Before taking the next scheduled dose, let the prescribing doctor know what happened. They can talk through options such as:

continuing Repatha with monitoring,

adjusting timing or evaluating for other causes of symptoms, or

switching to another cholesterol-lowering approach if needed.

If you’re feeling better now and symptoms weren’t severe or dangerous, many people do end up continuing the medication, but it’s safest to check with your provider first.