@tvane27 I understand about the estradiol. Women were told that it caused cancer. I remember growing up with them saying that estrogen caused cancer to grow in women. That is a old way of thinking and has been out dated. We need estrogen for our health as we age into menopause and beyond. These hormones help in the aging process and loose them as we age we need them for normal female aging process. I listen to podcast by women doctors for information. We were raised in a male dominated medical age, we were not truely represented (women) properly. Women are now learning that things we were told and taught is no longer or or was never really true in the first place. I listen to two different podcaster (Mindy Pelz, and Cynthia Thurlow) who are female doctors and are trying to teach us how to live in a way that supports our bodies as we age.