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Hans, thanks for this post! I have had radiation and cryotherapy, but despite negative PET scans and biopsies, my PSA keeps rising. I have a teleconference with my urologist in a few hours, and he's already told me that I will need ADT therapy. My reaction is to say let's just take a chance and see where this goes (I'm 74, so how much longer do I have anyway?), but I know I can't do that to my wife, kids, and grandkids. The thought of ADT is giving me cold sweats (which may be worse than hot flashes), but reading your post helps on a number of levels. I just want to let you know that.

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Replies to "Hans, thanks for this post! I have had radiation and cryotherapy, but despite negative PET scans..."

@mzs
I’m 78 and been on ADT for eight years. Had really bad, hot flashes in the beginning, but not everybody does. There are a number of ways to stop the hot flashes, If you have them, come back and ask for help.

Never had fatigue, I run a mile twice a day and go to the gym three days a week. That keeps my muscles in shape because the first thing that happens with ADT is you get A belly because those muscles deteriorate first and then your other muscles start to go. Doing weight training three days a week for one hour offsets it. Nine months ago, I couldn’t get off the floor without pulling myself up on a bed or a chair or a fence, Four months after I started, I could get off the floor without help. You definitely want to have a DEXA scan to see how good your bones are before you start ADT. You should also get a blood test to see how much testosterone you have so you know where you can probably reach, when you stop ADT.

If you have a choice and you really should try to ask for it you should be on Orgovyx for ADT. When you stop, your testosterone comes back much quicker and it does have fewer side effects.