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Anyone experience sore feet or heel pain from Letrozole?
Breast Cancer | Last Active: Dec 27, 2025 | Replies (17)Comment receiving replies
I've been taking Letrozole for about a year and a half, and this past summer I started having heel pain. It was especially bad at night because I couldn't find a comfortable way to lie down. I also have a bone bump on my heel. Anyway, I did change shoes and that helped some. It now only comes and goes. I take Tylenol and Oxycodone for most pain.
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@sassega
If it is on your Achilles tendon, on the back of your ankle, it is probably Haglund deformity.
I had an injury years before my cancer diagnosis but a bump developed after treatment.
I went to PT and that helps with the pain. (It looks like a small golf ball on the back of my ankle).
The PT exercises and walking help.
I won’t lie - when it acts up, the sudden pain is debilitating.