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@ropnrose

I'm just wondering if your infusion dose of Actemra or the time interval between infusions ever changes. I haven't had any infections or side effects from Actemra so everything stays relatively constant. My rheumatologist has made some adjustments to my dose and infusion schedule to accommodate travel , holidays and various things like that. I'm on an every 4 week infusion schedule but I have gone as long as 7 weeks. My inflammation markers were increasing at 7 weeks so my rheumatologist says I shouldn't go any longer than 6 weeks between infusions.

My actual infusion dose was easy to adjust too. I was on the highest dose recommended based on my weight which was 8 mg per kg. However, now I'm getting 4 mg per kg which is the minimum recommended dose. What I'm trying to say is that your Actemra infusion dose can be adjusted up or down as needed.

For patients receiving Actemra intravenous, you can get anywhere between 4 mg per kg and 8 mg per kg as clinically appropriate. My rheumatologist doesn't plan on ever stopping Actemra as long as it continues to work for me and it keeps me off Prednisone . I have been on Actemra for 7 years and completely off Prednisone for 5 years.

The following link discusses how both the dose and the interval of Actemra infusions are adjusted for RA patients.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4999578/

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Replies to "@ropnrose I'm just wondering if your infusion dose of Actemra or the time interval between infusions..."

@dadcue Due to my WBC continually getting lower and my respiratory infections, my rheumatologist just lowered my dosage. I was on 6 mg/kg. I just had my first lowered dose of 4 mg/kg. last Tuesday. My infusions are every 4 weeks. Before this, he talked about starting my 'taper' in Jan. 2027. Looks like I just started my taper. Hopefully, my WBC will improve, as well as my immunity.

I've never been completely pain-free. I took my last dose of Prednisone the first week of November, about the same time as my November infusion. The time between that infusion and my December infusion, my pain increased. Knees, hips, shoulders. After my infusion, it improved a bit. Are you pain-free?