I am on my 3rd month of daily Tymlos Injections. Similar to your situation, I was surprised to learn that osteoporosis in my lumbar spine currently makes surgery too risky.

Regarding the cost, I too have Medicare Parts A, B, Gap/Supplement and Part D Prescription. A pharmacist recommended I apply for copay assistance. The application was easy, and acceptance was fairly fast. My application results = zero copay. $0/month. I really didn't think we would qualify so I encourage you to try. Try searching for: Radius Assist Patients Assistance Program, and/or Tymlos Patient Savings Card, or Prescription Hope. Hopefully the other bone building meds offer assistance, if needed, too.

I do my injections in the morning and have not noticed any negative side effects thus far. Blessings