@trina24 I have been on Actemra for 6 months and already it has started to attack my liver. My doctor lowered the mg from 6g to 4mg and now the pain has returned inside my head again. The doctor said previously that I would be on Actemra for 2 years. I am now wondering if I will be able to make that. I was diagnosed with GCA in May of this year. Previous to that I had PMR for 1 1/2 years and then 6 months of remission when I was hit again with GCA. I was on prednisone with the PMR for 1 1/2 years and with GCA for 6 months as a result of the prednisone I have been diagnosed with Glaucoma a few weeks ago. I hope you fair better than me on the prednisone and Actemra.