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ProstoxUltra & Prostox CFRT both high risk-switch to RALP?
Prostate Cancer | Last Active: 14 hours ago | Replies (18)Comment receiving replies
@wwsmith you said “ With an RP there is a greater chance of ultimately experiencing a distant metastasis than there is from being initially treated with radiation.”
There seems to be some reasoning behind this, but, Tests have shown that people that have RP’s are more likely to have better survival after having a DM. This also seems to be true in more advanced cases, not cases were the cancer as isolated to the prostate without advanced issues.
Recent studies, especially for high-risk localized prostate cancer (PCa), suggest radiotherapy (RT) may actually provide a lower risk of distant metastasis (DM) compared to radical prostatectomy (RP), contradicting the idea that RP is better; some research indicates RT-based treatment significantly lowers DM risk, while other analyses show similar overall outcomes but with RT potentially controlling progression better in unfavorable cases, though RP offers better survival after metastasis develops.
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@jeffmarc
Thanks Jeff for listing different results of different studies which all point to a finesse needed in making decision on INDIVIDUAL bases.
There is just no one general guidance for every possible case. There are so many subgroups in each stage and group and it all also depends of age, comorbidities, life expectancy, etc etc. , as well as of personal preference, lifestyle and personal risk tolerance.
If we knew what we know now - that gland would have been out at 3+3 when micro mets are really non existent. We trusted our incompetent urologist who did one single biopsy in 7 years and that is why we ended in this mess of 4+5 at the end, and with all AS and MRIs etc etc , AS failed 100%.
My husband recovered so nicely after RP (knock the wood) and it was always our preferred treatment. When he got his first 3+3 we decided that he will have RP if there is any movement in wrong direction (a single 3+4 core), but alas, no additional biopsy was ever done since his genetic results showed super low risk *eyeroll.
PC is a "low risk" at that particular moment of time- in the next year or two it can become aggressive just like that , and we did not know that : (((. So, again, IF we knew what we know now - RP would have happened at 3+3 .