Connect
← Return to Recovery of testosterone and side effects after stopping ORGOVYX
Discussion
Recovery of testosterone and side effects after stopping ORGOVYX
Prostate Cancer | Last Active: Dec 7 11:00am | Replies (31)Comment receiving replies
As I understand it, the low testosterone causes the side effects and not the Lupron. This raises the issue of why doctors keep giving Lupron or other ADT to men who have already been chemically castrated by the ADT. Studies show that more than 50% of men will never recover their testosterone levels once treated, yet many men take ADT for many years. My side effects seemed life threatening to me and I had testosterone levels around 200 before treatment. Now 5 months after stopping Lupron I still have serious side effects. Some are getting better while some are getting worse. My PSA is < 0.1 and testosterone < 9 after 5 months.
Replies to "@jeffmarc As I understand it, the low testosterone causes the side effects and not the Lupron...."
Connect
@pesquallie
It’s not that they won’t get testosterone back at that. It’s that they won’t get it back at the same level it was before.. Yours was very low to start.
My brother was on it six months and it took him almost a year before most of the hot flashes stopped.
Check out this study that compares Orgovyx to Lupron patients testosterone return time.
https://www.sciencedirect.com/science/article/pii/S2588931123002900
One thing that it finds is that people just don’t recover from Lupron very quickly
Overall, 74 of the 137 men in the relugolix cohort recovered to testosterone >280 ng/dl, with a median time to recovery of 86.0 d (95% CI, 65.0–92.0), versus two of the 47 men in the leuprolide cohort, with a median time to recovery of 112.0 d