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Metastatic bone cancer with unknown primary: Anyone else?

Cancer | Last Active: Dec 14, 2025 | Replies (25)

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@coco46 ~ Hello! Yes, a biopsy was performed, also a liquid biopsy was done, blood testing, CT, etc. If theres a test or procedure, I've done it. Nothing pops up on a PET scan as well. I'm having another PET scan on Monday, but I don't really expect any new news. My Oncologist says about 10% of cancers are of unknown primary, and we may never know. Which in my opinion is the worst! I can't find any trials, support groups or anyone that has unknown primary, and the prognosis is terrible. I'm having a second opinion with UCSF in a week or so. I guess we'll see... Thank you for the reply and information, I appreciate it. (Sorry for the rant!)
P.S. what is IHC testing? 🤔

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Replies to "@coco46 ~ Hello! Yes, a biopsy was performed, also a liquid biopsy was done, blood testing,..."

@jobo1031 Immunohistochemistry, they use it to test the tissue samples for different antigens and responses. For me they used it to figure out the more specific type of breast cancer I had.

I hope and pray they can figure out what ever the best treatment is for you, even if they are not sure what the type of cancer is.