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Continued Monitoring or Biopsy?

Prostate Cancer | Last Active: 1 hour ago | Replies (21)

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Profile picture for jeff Marchi @jeffmarc

@ezupcic
What you say is true, a lesion is not necessarily there, but there is a specific area abnormality found to get a PIRADS 2 score, So that could be targeted in a biopsy just like a lesion.

AI says the following

Yes, a PI-RADS 2 score indicates a low probability of clinically significant cancer, but it's assigned to specific suspicious lesions or areas (like linear/wedge-shaped abnormalities in the peripheral zone, often from prostatitis) that have certain characteristics, not just a completely normal prostate, though a score of 1 is very low likelihood, and PI-RADS 1 or 2 often means deferring biopsy. You need to have a focal finding (a "lesion") that meets PI-RADS 2 criteria for that specific score to be given, rather than just a "normal" scan, which would be a PI-RADS 1.

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Replies to "@ezupcic What you say is true, a lesion is not necessarily there, but there is a..."

@jeffmarc interesting. My urologist said there would be nothing to target but if I understand you correctly you are saying there is a focal finding which is what makes my score a Pirads 2 that could be targeted and the MRI scan could be utilized to do that?

@jeffmarc my AI saying the following:

"With a Pi-rads 2 MRI and a PSAD of 0.086, the odds of clinically significant cancer are generally low. Your family history nudges risk up, so a reasonable plan is to refine risk using biomarkers and trends, and proceed to a systematic transperineal biopsy only if those signals become concerning or if you prefer definitive sampling now for peace of mind."

So back to square one. Biopsy now for peace of mind potentially or follow trends and continue with biomarkers..........