@jnj When you indicated “PI- RADS 2- assessment 4”, I didn’t quite understand what that meant.

If it’s PIRADS 4, that indicates “ High (clinically significant cancer is likely to be present).”

But, that is still not a diagnosis of prostate cancer - it represents a statistical probability. (Many of us had PIRADS 4 (or PIRADS 5); I was 65y when I had treatment for that.)

You still need the biopsy for a diagnosis.