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Brinsupri follow-up

MAC & Bronchiectasis | Last Active: 10 hours ago | Replies (328)

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Profile picture for deestrada @deestrada

I started Brinsupri in September. I now am experiencing the skin thickening on my feet. Very annoying. My dermatologist has me on a steroid cream and an exfoliant for 14 days. Frankly I'm not sure if the condition can be eradicated while on the drug. I called the Enlighten support patient line and there is no detailed information on patient experience. Anyone else experiencing feet problem?

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Replies to "I started Brinsupri in September. I now am experiencing the skin thickening on my feet. Very..."

@deestrada So far I have not experienced skin thickening but have only been on Brinsupri for 10+ weeks. Would it be possible to say more about your symptoms? How did you noticed the skin thickening on your feet? Is it only on the bottoms of your feet or all over? Does it interfere with your walking, or itchy or other?

My fingertips feel rough but that's par for the course each winter it seems especially with the cold snap. The soles of my feet are different in winter than summer too, less exfoliation it seems.

I hope you get some relief with what the dermatologist gave you!

@deestrada I started taking the 25mg Brinsupri on October 1st. I noticed within 2 weeks of starting that the palms of my hands were feeling funny. I mentioned it to my dermatologist, and she said not to worry about it unless it got worse. Now, my palms are always itchy, and the skin feels dry and rougher. I noticed in the last couple of weeks that the soles of my feet were itching as well. I spoke with the PANTHERx pharmacist yesterday and she said that those are the first symptoms of hyperkeratosis (skin thickening).

I have reached out to my pulmonologist, asking if I can temporarily stop the Brinsupri, since I have also been on antibiotics for pneumonia since September. I would like to clear the pneumonia before resuming the Brinsupri.