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Tymos and kidney function?

Osteoporosis & Bone Health | Last Active: 1 hour ago | Replies (14)

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Profile picture for kathysueweeks @kathysueweeks

I’ve been on Tymlos for four months and was shocked to find my GfR went down to 42 in that short time! I’m very worried and scared that this is a permanent change. I see my endocrinologist in two weeks and have started researching this issue too.

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Replies to "I’ve been on Tymlos for four months and was shocked to find my GfR went down..."

@kathysueweeks

It is staggering what we don't know, isn't it? After I posted about this in August 2024, my eGFR declined slightly further in early 2025, coming in at 60 and then 59 (endo and internist, different labs), which isn't terrible given my age but still representd a drop of more than 10 points from Feb 2024 to Feb 2025 (from 72 to 59). My endocrinologist speculated that I was perhaps dehydrated when the blood for the metabolic panel was drawn, since it was late in the morning and I hadn't had anything since the night before, so I've made an effort to drink more water during the day and in fact my eGFR has rebounded in the two latest tests (9/2025 and 11/2025), to 71 (!) from one lab (endo) and 66 from the second lab (internist). BUN and albumin are both stable and well within normal limits (although BUN dropped when I started drinking more, which seems a normal reaction). So who knows?

Good luck to you. I'll be interested in what your endo has to say.