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Actemra usage and high iron

Polymyalgia Rheumatica (PMR) | Last Active: Dec 4, 2025 | Replies (6)

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Profile picture for jabrown0407 @jabrown0407

Very high iron in your blood is likely caused by interestingly enough, low Hemoglobin in your CBC panel - meaning you are anemic. I was diagnosed with Anemia of a Chronic Disease likely caused by PMR back in 2019. At the time my Ferritin levels were over 1,100 ng/mL, normal is below 200. Do not take any iron supplement or eat foods high in iron - it can cause severe problems including death if you are having problem metabolizing iron.

The iron is available in your blood if you have high Ferritin levels, your body is not absorbing it correctly right now. How your blood absorbs the iron in your blood is like all other metabolic processes a complex. Without going into details just know it is not simple. I would encourage you to research this some online then talk with PCP to understand what you can/should do to help manage it.

When I am on prednisone my anemia gets better. This September my Ferritin was 140, normal. Last year it was high. It does pop in and out of normal now.

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@jabrown0407 thank you for your reply and advice, I will meet with a hematologist next week for further testing