@pcjourney25 hi Kathy. My cancer was in the head but encasing/abutting arteries. I got the same advice to do FOLFIRINOX then talk about surgery. The program I did was several hours in the infusion center day 1, take home a pump then come back day 3 for it to be removed and to get a shot to stimulate blood cells. I do suggest getting more than one opinion from experienced surgeons on the surgery front. After the neoadjuvant treatment cycles one surgeon was good to go and the other wanted to do radiation before considering surgery. I did have the Whipple. and thankfully it was successful including reconstruction of an artery.