Choices for dosage, in many areas of medicine, if not all, are very important..people are different in so very many ways ! Sometimes, one can use a pill splitter, but not for all meds…;I have read that the generic for Fosamax comes in different sizes…that could help some people…some people don’t inject the whole dose of injectables….chemo is often adjusted as one goes along…the more of us who advocate for dosage reductions, the better for all.