Hi @sunny18 - I wanted to let you know I moved your post here so that you could talk with others who have taken levetiracetam (Keppra) or been around a friend or family member who took it and can speak to experiencing agitation with this medication.

- Side effects from Keppra? https://connect.mayoclinic.org/discussion/does-anyone-know-if-intense-keppra-side-effects-are-normal/

Please meet @keppraeffect @hippele @royanthony @gratefulbob and others in this discussion.

Were you saying, sunny18, that you are still struggling with the diagnosis? If so, will you share a bit more about that?

@sunny18
Vitamin B6 helps some people with anger and aggression issues caused by Keppra. Ask your doctor about it.
Jake

@sunny18

I’ve been on Keppra extended release for years with success. I’ve had no possible side effects. except I sleep a little more than I used to.

@sunny18
Welcome to our group!
Yes, Keppra can definitely cause mood-related side effects for some people. Thankfully, I haven't experienced those since starting Keppra alongside Epidiolex in December 2024.
As my doctor reminds me, everyone responds differently – what works well for one person might not work for another. Side effects vary from person to person and often depend on the dosage prescribed. When I first started Keppra at a higher dose, I had several side effects (not mood-related ones), but they became much more manageable once my dosage was reduced and customized.
For example, Tegretol (carbamazepine) sent me into a depression, so I had to switch to something else. But I know many people who do really well on it!
I'm curious – what kind of epilepsy do you have?
Chris