Connect
← Return to Continued hormone therapy? or not?
Discussion
Continued hormone therapy? or not?
Prostate Cancer | Last Active: 15 hours ago | Replies (12)Comment receiving replies
@web265
In my case they didn’t, after surgery. I was a 3+4 before surgery and a 4+3 after. I went 3 1/2 years after surgery before my PSA started rising. Pretty sure ADT would not have been given to me that long if they did recommend it.
Below guidelines, highlight the fact that in your case, you would need two of these three things before ADT would be recommended. PSA 10-20, GG2 or 3, T2b-c. So, where do you fit Based on your past history?
Here are current NCCN Guidelines in 2025. They now suggest 0 (zero) months of ADT for low intermediate (GG2); 4-6 months for high intermediate (GG3), and 18-36 months for high risk (GG4 and 5). Actually, the footnote suggests ADT + abiraterone for T3b with lymph node involvement.
The meta-analysis suggests:
* 0 months for 1 intermediate factor (PSA 10-20, GG2 or 3, T2b-c)
* 6 months for 2 or more intermediate factors (PSA 10-20, GG2 or 3, T2b-c)
* 12 months for NCCN high risk (PSA >20, GG4 or 5, T3 or 4)
* undefined for NCCN very high risk (2 or more PSA >40, GG4 or 5, T3 or 4)
Replies to "@web265 In my case they didn’t, after surgery. I was a 3+4 before surgery and a..."
PSA 10-20 (check)
GG3 (check)
pT2c,pNO
So, as I understand it, (much less than you do), On that scale, I'd be between 6 and 12 mos somewhere.
Thanks for gettin' back. Was just curious.
Connect
@jeffmarc
My PSA was 18 before the surgery, gleason was 3+4 so that would be GG2, the only thing I am not sure of is the T2b-c, the cancer was contained in one area of the prostate but after removal and PET scan, it showed up in the area of the removal, so some had escaped the gland. All clear after radiation and my PSA has maintained a .006 score.