Hi @jump, Welcome to Mayo Clinic Connect. You mentioned you have to be on prednisone the rest of your life along with gabapentin and pain meds. I have small fiber peripheral neuropathy but I only have the numbness and there are no drugs that help with it. I take some over the counter supplements but it's not a cure and doesn't make the numbness go away. I do believe they may have slowed down the progression but it's subjective on my part. While I don't have pain with my neuropathy, I have had 2 occurrences of polymyalgia rheumatica (PMR) that were extremely painful and was on prednisone both times but was able to taper off once the PMR went into remission. I think each of us deal with pain a little different and a lot of members here have found different treatments that help.

You may want to read the following discussion and see how other members are dealing with the pain associated with neuropathy.

Groups > Neuropathy > Living with Neuropathy – Welcome to the group
— https://connect.mayoclinic.org/discussion/living-with-neuropathy-welcome-to-the-group/

Are you able to share a little more about your diagnosis and any other treatments you've tried?