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Peripheral Neuropathy and benign fasciculation syndrome.

Neuropathy | Last Active: Dec 8, 2025 | Replies (111)

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Profile picture for giaodonnell @giaodonnell

July of this year, I noticed my calf muscles twitching on both legs (not all day) - by August they were twitching around the clock- localized to calves. I went to Dr- ordered a bunch of bloodwork and told me to come back in 3 months after taking B12. B12 was on low side but not out of range. 3 weeks later I went back b/c not only was their muscle twitching I was experiencing parathesis in my lower legs and arms and they sent me to a neurologist.

I failed the vibration/temperature screening- he told me I had PD and sent me for extensive bloodwork. Only thing that was a little high but not out of range was by B6- Came back for EMG and it was clear- he told me I most likely had Small Fiber neuropathy and told me to take soluable B12, stop alcohol all together ( I drink occasionally) and sent me on my way.

I went back to my primary and now have a 2nd neurology appt b/c she doesn't like the muscle twitching. I'm 53 year old woman- I work out 3-4 times a week and can not figure out what the root cause is. My legs are either a burning sensation, constantly twitching and now around my ankles feel numb. Sometimes I get the same sensation in my hands/arms but not everyday.

Anyone else have the same experience where it started with fasciculations and then the symptoms of neuropathy started?

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Replies to "July of this year, I noticed my calf muscles twitching on both legs (not all day)..."

@giaodonnell Welcome to Connect. It doesn’t sound like your doctors have thought about any spine issues yet. I had those same symptoms that were for me generated by some disc problems in my spine, mostly it was cervical with slight spinal cord compression, but I also had a bulging lumbar disc. I did have a cervical fusion which resolved the issues. My first symptom of spinal cord stenosis was a pain in my ankle when I turned my head. That was caused by bone spurs moving across my spinal cord. A spinal cord compression issue in the neck can cause leg symptoms. There could also be arthritis where a nerve exists the spinal cord that could cause symptoms specific to that nerve. Spine issues do tend to get worse with aging. Hopefully your doctors will find an answer and solution for you.