Connect
← Return to Tymlos causing belly fat?
Discussion
Osteoporosis & Bone Health | Last Active: 1 day ago | Replies (133)
Comment receiving replies
Has anyone seen a good explanation for why Tymlos can cause belly fat? There must be some process involved to cause this. Is that process beneficial or not?
Replies to "Has anyone seen a good explanation for why Tymlos can cause belly fat? There must be..."
Connect
@normahorn I did some research using AI on this and found this possible explanation:
“Hormonal Signaling Crosstalk (Wnt & IGF-1)
Anabolic drugs work by activating growth pathways like Wnt signaling and IGF-1 (Insulin-like Growth Factor 1) to build bone.
Mechanism: These same pathways are active in adipose (fat) tissue. While the drugs are designed to target bone, "off-target" signaling can occasionally promote the maturation of fat cells (adipocytes) in specific areas, such as the abdomen.
Result: This can lead to localized fat storage even if your overall metabolic rate and glucose levels remain stable.”