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Tapering off of Prednisone

Polymyalgia Rheumatica (PMR) | Last Active: Feb 28 5:49am | Replies (313)

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@phoenix0509

@johnbishop , this is my first major pain flair and I will discuss with Rheumatologist at next tele-medicine visit. When I say major flair I mean almost total body pain it seems and it is not responsive to small prednisone dosage changes nor is it terribly responsive to pain medicines. I also have SFN and my feet and hands hurt from that, but nothing like PMR. I find PMR to be one of the most painful conditions I have experienced along with overwhelming fatigue. John are you aware of anybody who has entered into a clinical trial
of Tocilizumab (Actemra) for PMR ? Thanks

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Replies to "@johnbishop , this is my first major pain flair and I will discuss with Rheumatologist at..."

@phoenix0509, I think @paddington has posted about taking Tocilizumab (Actemra) injections for GCA and may be able to offer some insights on it's use. I found an article that mentions it's use for PMR but I'm not sure who has taken the drug to treat PMR.

Tocilizumab Found Steroid-Sparing in PMR - A second small study showed benefits for tocilizumab in polymyalgia rheumatica:
-- https://www.medpagetoday.org/rheumatology/generalrheumatology/57894?vpass=1