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Tapering off of Prednisone

Polymyalgia Rheumatica (PMR) | Last Active: Feb 28 5:49am | Replies (313)

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@johnbishop

Hi Rex @rexbeer, welcome to Mayo Clinic Connect. Prednisone is that magic pill for arthritis. I have polymyalgia rheumatica (PMR) which is currently in remission. I have had two occurrences of PMR six years apart. Both were treated starting with 20 mg prednisone dosage. The first time it took me about 3 years to taper off of prednisone. The second occurrence it took me about 1-1/2 years to taper off. The biggest side effect I had was weight gain - about 50+ pounds the first time but knowing that the second time I was able to make some lifestyle changes that helped me control the weight gain. I was able to keep it between 5 and 10 pounds. Mayo Clinic has some information here:

Prednisone and other corticosteroids
-- https://www.mayoclinic.org/steroids/art-20045692

Two of the long term effects I already have but I'm not sure if the two uses of prednisone were to blame - thin bones (osteoperosis) and thin skin. I'm forever bumping into things with my arms and surprised to see a trickle of blood or a wound and I never even felt what caused it. I had figured it was part of my aging at 75. I think it might depend on if you are in a high risk group but I'm not sure. I did find a study that talks to this point a little...

Monitoring long-term oral corticosteroids | BMJ Open Quality
-- https://bmjopenquality.bmj.com/content/6/2/e000209

Have you asked your doctor what they think about any long term side effects that might apply to you?

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Replies to "Hi Rex @rexbeer, welcome to Mayo Clinic Connect. Prednisone is that magic pill for arthritis. I..."

John that was a helpful post or three. I've only just found the forum. I suffer from HUVS but seem to be in remission. After taking Prednisone for over 10 years I suffer from thin skin (cataracts and glaucoma as well of course). I've just about got down to 5mg after 4 months. I'm interested to know if my skin will recover?