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Elevated Serum B 12 levels and its relevance

Heart & Blood Health | Last Active: Apr 30 6:56am | Replies (15)

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Profile picture for kdalda75 @kndaustin71

@pb50 &@gently Thanks so much for the responses. Labs were drawn as first time visit to a new Concierge Internal Medicine/Functional visit in August 28,2025. B12 was elevated at 1707 (range for Lab Corp 232-1245), SGOT 58, elevated SGOT at 55 (0-40 range) Renal panel WNL - Abdominal ultrasound was negative. Repeat lab for f/u on 11/19/2025 Vitamin B12 was 1836.
I stopped the multivitamin, did some deep-dive research and feel that further testing needs to be done to evaluate the elevation of B12. Most of the NIH articles and others I have read from reputable sources have mentioned hard tumor in liver, pancreas, colon along with blood disorders of the malignant type. Cannot seem to get the physician interested in evaluating further. Wondering What specialty I should pursue....hematology perhaps. The 45 years of nursing in me tells me yes - 2nd evaluation. 20 years of the 45 were spent as a Director of Nursing so I am used to investigating abnormal labs and working with the physicians for answers. All opinions welcome

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Replies to "@pb50 &@gently Thanks so much for the responses. Labs were drawn as first time visit to..."

@kndaustin71, I suggest (without opinion) asking the "concierge" physician to order Anti Nuclear Antibody testing (ANA) to rule out specific autoimmune systems. You should be able to obtain this order without seeing another physician.

@kndaustin71
Fascinating. I spent a dozen years in neurophysiology and diagnostics before transitioning to the risk management side of service delivery. But once you develop a diagnostic brain, you’re stuck with it 🙂
I have had a few opportunities to observe concierge medicine that were treating friends and family. I’m curious - were you pleased/impressed with thebone you saw? My impression is that they see their key value proposition as availability and affability and assume that is what you are willing to pay up for - but I wouldn’t care if they were mean as hell if they were brilliant diagnosticians.

I absolutely agree you need to run this to ground. In this case I am less useful than Google I’m afraid. But I would figure out who the Ace internist in town is and get your primary to pull strings to get you a referral.