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Anyone with aggressive prostate cancer (Gleason 9) and low PSA?
Prostate Cancer | Last Active: Dec 5 12:41pm | Replies (21)Comment receiving replies
Did you have quarterly PSA tests on the first 9 months post-radiation treatment? I will have my post-SBRT’s 3rd PSA test in January 2026, at which time I will be four months off ADT (Orgovyx) already. My oncologist said that my nadir will be the last reading before my PSA begins to rise. I suppose if it’s higher in Jan/2026 compared to Oct/2025, then my Oct PSA 0.22 will be my nadir. I am hoping though that January will be >0.22 or even be undetectable. My oncologist said that it could be higher given that testosterone level recovers fast after stopping Orgovyx, but I shouldn’t worry if the PSA rise is explainable with a corresponding testosterone level getting higher. With radiation alone without ADT, it can take up to two years (or more) before PSA becomes undetectable.
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@vircet So true ...Good point Sir . With my 22 session of radiation ( EBRT about 3 years after surgery with no ADT ) , my PSA started at 0.14 , then bounced around . No I am at 2.5 years post radiation my PSA hovers in the 0.066 - 0.040 range . it just goes sideways now . But it took a long time for it to sort of bottom out ! Just the way it works I gather ? Thanks Sir . James on Vancouver Island .
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@vircet
Thank you so much for taking the time to reply.
I have had the quarterly PSA tests, my last one was just 2 weeks ago 0.008. I guess the next important test result will be in 6 months time. Then I will have 3 months without an injection.