@jlharsh
Very interesting thank you for sharing this. The part in which they weed out Statin intolerant individuals before accumulating the data in the trial was an eye opener! I didn't experience Myopathy while on the traditional class of statin. I did have increased joint stiffness. My Main intolerance was a form of diminished Neurotransmission. Traditional Statin overtime gave me a form of fogginess. The PCSK9/Repatha/Evolocumab gave me a form of mood swings. With both medications each have a completely different molecular property/structure but demonstrated similar side effects regarding cognitive or neurotransmission. I find this fascinating. Then you explain this to Pharma people, or Cardiologist, and it doesn't present itself in anything they have been given to read. The response: This is not typical. The one denominator/variable was this neurotransmission reared its head in all my history after my numbers plummet. I experienced this side effect with total cholesterols a little over 100 and LDL getting into the 40's and while on the Repatha LDL of 37. More severe with the Repatha, I am not a doctor but if this doesn't explain some kind of correlation with certain individuals in which cholesterol numbers fall, then I must be missing something. In which I am not...