How to taper from 50 mg of pregabalin in the morning and evening?

@note8book
I am 75 yrs old and was on 200mg/day for 9 months. I started to wean down under my psychiatrist in February 2025. We are now in November. I reduced 25mg every 4 weeks. When I got to 50mg I started to reduce by about 15% every couple of weeks or so. I am now at 17mg. My psych prescribed liquid Pregabalin 200mg/20ml. I ask Chat Gpt to do the conversion. I use a 1ml syringe to measure it out. It is trial and error how much I drop - but I am trying to stick to the 15% drop every 10-15 days. At this rate I won’t be finished till April 2026 but I may be able to finish earlier depending how I feel (intend to stop at 1mg or 2mg Pregabalin). It hasn’t been great throughout and some uncomfortable days but I try to keep busy and it passes. If it gets really uncomfortable I will take a Valium but am feeling so much better at these lower doses I have only taken one or two lately. I have high blood pressure too (I take medication for it) but it doesn’t seem to have affected it. I know a lot of people decrease quicker and some with no symptoms but I think as we get older our minds get weaker and we are sensitive. The way I am doing it is long and slow but it’s meant to be the safest way and at least I can carry on with my life even if am not always feeling A1. You should do this under a good GP or a psychiatrist as it’s important to have some support. This is how I am doing it anyway. I felt like you with the brain fog, tiredness and generally felt yuk! I will be relieved to be off it! Good luck!

Sorry. I see you haven’t been on Lyrica/Pregabalin for too long but you will still need to taper. You may be able to go faster than me. Your body will tell you. I wouldn’t think it could affect your blood pressure but obviously check with your doctor.

I decided not to try to wean off the Lyrica. It is beginning to help some. I upped the morning dose to 75mg without talking to my neurologist since I don't see him until April of 2026. It is helping me and my body has adjusted to the upped dose and I am dealing well with the drousy effect. I am slowly beginning to get back to my normal life except for my blood pressure problems. Even though I take BP meds three times a day my BP still spikes up over 200 sometimes I just take some clonodine to bring it down. That's what my cardiologist NP told me to do. I have an appointment with a pain management specialist later in the year and I hope he will give me some shots in my lower back for back pain. I have fibromyalgia and have to deal with pain from that every day and have for about 30 years now. I also have degenerative spine and a bulging disk in my lower back. I am still mobile and try to stay active as much as possible. I'm still able to walk around at Walmart to do my shopping so I am thankful for that. God has blessed me so much. Praise his Holy Name.
On Thursday, November 27, 2025 at 02:28:53 PM CST, Mayo Clinic Connect < nf+34fc0ccb+86661779@n1.hubapplication.com> wrote:

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| @angelfru1t mentioned you in comment on Thu, Nov 27.

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@note8book
I am 75 yrs old and was on 200mg/day for 9 months. I started to wean down under my psychiatrist in February 2025. We are now in November. I reduced 25mg every 4 weeks. When I got to 50mg I started to reduce by about 15% every couple of weeks or so. I am now at 17mg. My psych prescribed liquid Pregabalin 200mg/20ml. I ask Chat Gpt to do the conversion. I use a 1ml syringe to measure it out. It is trial and error how much I drop - but I am trying to stick to the 15% drop every 10-15 days. At this rate I won’t be finished till April 2026 but I may be able to finish earlier depending how I feel (intend to stop at 1mg or 2mg Pregabalin). It hasn’t been great throughout and some uncomfortable days but I try to keep busy and it passes. If it gets really uncomfortable I will take a Valium but am feeling so much better at these lower doses I have only taken one or two lately. I have high blood pressure too (I take medication for it) but it doesn’t seem to have affected it. I know a lot of people decrease quicker and some with no symptoms but I think as we get older our minds get weaker and we are sensitive. The way I am doing it is long and slow but it’s meant to be the safest way and at least I can carry on with my life even if am not always feeling A1. You should do this under a good GP or a psychiatrist as it’s important to have some support. This is how I am doing it anyway. I felt like you with the brain fog, tiredness and generally felt yuk! I will be relieved to be off it! Good luck!
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