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Started Repatha - Side Effects
Heart & Blood Health | Last Active: Nov 30 5:26pm | Replies (441)Comment receiving replies
@johnjtgg, you may find this podcast valuable. It includes a background as to why initial statin trials were misleading and how that impacts both doctors and patients. I am I patient at Mayo Clinic MN and the approach described as “looking like how blood pressure is treated” resonates with me. My numbers are controlled for the first time in my life. I get Inclisiran injections twice a year and my last one actually made me feel better. Additionally, I take lower doses of drugs I’ve tried before and had said, “never again”. Keep learning!
- Mayo Clinic re: Statin Myopathy https://cardiovascularcmemayoclinic.podbean.com/e/statin-myopathy/
@llynch17056, I love how you keep pushing to figure out how to keep moving forward. I look forward to what you learn from next week’s stress test.
Have any of your doctors talked to you about finding someone specializing in statin (cholesterol drug) intollerance?
Replies to "@johnjtgg, you may find this podcast valuable. It includes a background as to why initial statin..."
@jlharsh
Very interesting thank you for sharing this. The part in which they weed out Statin intolerant individuals before accumulating the data in the trial was an eye opener! I didn't experience Myopathy while on the traditional class of statin. I did have increased joint stiffness. My Main intolerance was a form of diminished Neurotransmission. Traditional Statin overtime gave me a form of fogginess. The PCSK9/Repatha/Evolocumab gave me a form of mood swings. With both medications each have a completely different molecular property/structure but demonstrated similar side effects regarding cognitive or neurotransmission. I find this fascinating. Then you explain this to Pharma people, or Cardiologist, and it doesn't present itself in anything they have been given to read. The response: This is not typical. The one denominator/variable was this neurotransmission reared its head in all my history after my numbers plummet. I experienced this side effect with total cholesterols a little over 100 and LDL getting into the 40's and while on the Repatha LDL of 37. More severe with the Repatha, I am not a doctor but if this doesn't explain some kind of correlation with certain individuals in which cholesterol numbers fall, then I must be missing something. In which I am not...
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@jlharsh no, no one has directed me to someone that specializes in statin intolerance. I’m looking for that though. I am also hoping the Terzepitide will lower my LP(a). 🤞🏻