@pesquallie Testosterone, hormone and androgen are all the SAME in this article. ADT blocks all of them.
So in early disease, blocking T is beneficial…it stops the cancer…however, in late stage it can produce the OPPOSITE effect and promote its growth. This is why it is called contradictory because giving T to a late stage patient should make it worse, not better. But they’ve found that it does, indeed, work by forming an odd receptor site molecule that blocks its growth. It’s weird, paradoxical and makes no sense, but there it is…
Hope that clears it up…
Phil