What PSA to expect 2-3 months after ending Radiation.

How long will you have been off of ADT at that 3-month point after ending radiation treatments? If the hormone therapy is still in your system at that point, your PSA will still be artificially suppressed due to the lack of testosterone.

In my case (see my attached PSA tracking chart), I had 28 sessions of proton radiation during April-May 2021, and had Eligard injections in April & July. My PSA remained suppressed by the ADT for 8 months after the radiation treatments ended, and then began to rise slightly, until it leveled out to where it is now.

(My official nadir in April 2022 was 0.198; though I did have a self-ordered PSA test done in February 2022 which was 0.13.)

Here is my PSA chart from before treatment to a few days ago. I had 5 mridian radiation treatments with no ADT.

@guerri2024
I did not have ADT. For those who did your PSA test will be much lower that those who did not.

Every lab (and it is important to know the facts of your lab not statistics of others) has different types of equipment and will different levels of PSA determined to be undetectable. At Mayo Jacksonville the lab there does not give PSA numbers below .10 At our lab numbers below .10 are considered undetectable.

So what ever lab you are having your PSA test done is real important to know what the undetectable number they use not statistics or other labs who might be different.

If you did not have ADT your PSA would slowly go down with radiation. Remember your prostate just went through WWIII and is not going to be happy for awhile and PSA will slowly go down. My PSA dropped on full point at 3 month after mark. Then went down to .12 at my 2.5 year mark.

You had ADT. My doctors told me ADT does not kill the PC. What it does is starve the PC from testosterones which it feeds on. So a person on ADT will have usually a higher rate of PSA going down that a person who did not get it along with PSA numbers being lower as long as on ADT. If you have a prostate you are going to have PSA numbers. My R/O said my goal was to keep PSA under 1 Mine right now is .12 so way under that goal.

These are questions your urologist and R/O should be answering for you. Have you asked them these? Most doctors don't automatically start giving information without questions. So important to asked your doctors every question you have then you can research or asked others for their personal experience who can share that with you.

The ADT will be a large factor in your PSA. You should be off it for at least 3 months before they retest, and in some men the effects can last much longer depending on the type of ADT used.
Also, remember that ‘everyone is different’ - can we EVER say that enough?
Your drop is going to be yours, not someone else’s; so please don’t stress if your first PSA is not drastically lower than the original reading, or if it’s not ‘undetectable’.
It can take many months to reach its nadir and as long as the trend is downward you’re doing fine.
Phil