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DiscussionADT, maybe not? Anyone opted out of ADT?
Prostate Cancer | Last Active: 29 minutes ago | Replies (84)Comment receiving replies
Replies to "I am trying to get a 2nd opinion concerning ADT duration. I am 75 yrs old..."
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@lamer25
Were you told you are pT3b? With seminal vesicle invasion that is the normal stage.
Here are the USA guidelines for ADT.
You should notice that T3 requires at least 12 months. Not 24 months however, with your other low grade prostate cancer issues. Some doctors like to be more careful about spread.
Here are current NCCN Guidelines in 2025. They now suggest 0 (zero) months of ADT for low intermediate (GG2); 4-6 months for high intermediate (GG3), and 18-36 months for high risk (GG4 and 5). Actually, the footnote suggests ADT + abiraterone for T3b with lymph node involvement.
The meta-analysis suggests:
* 0 months for 1 intermediate factor (PSA 10-20, GG2 or 3, T2b-c)
* 6 months for 2 or more intermediate factors (PSA 10-20, GG2 or 3, T2b-c)
* 12 months for NCCN high risk (PSA >20, GG4 or 5, T3 or 4)
* undefined for NCCN very high risk (2 or more PSA >40, GG4 or 5, T3 or 4)
Keep exercising that defeats the fatigue from ADT.