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High PSA, but MRI is negative. Biopsy or Not?

Prostate Cancer | Last Active: 7 hours ago | Replies (55)

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@jc76
Hi jc76

The original scan was a contrasting MRI. I think it came out pirads 1 or 2. So with poor MRI scan the doctor planned to use ultrasound to guide. Once on the table he inserts the wand and sees no shadows, nothing. Seeing nothing on the ultrasound scan , he actually said “this is an unnecessary procedure” and suggested we stop. I responded something is really wrong (due to hematuria) and we are here so lets do it. At this point the samples were essentially taken at random with no guidance.
I am glad I did the biopsy for sure. I understand biopsies can miss things however …nothing is fool proof. The surgeon (Dr Ahlering ) at UCI told me that 8 -10 % of us can get scan negative PC and it can go undetected until is is quite advanced.

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Replies to "@jc76 Hi jc76 The original scan was a contrasting MRI. I think it came out pirads..."

@beachflyer
For most of us the good news is that Scan negative PC is usually low grade Gleason 6, but for a small percentage of us it can be advanced which is why we need to gather all the information we can (including biopsies) prior to treatment and pay close attention to subtle clues. In my case occasional small brown spots in semen (hematuria) was a pretty good sign of trouble. Both my family physician (who is a friend) and Urologist dismissed the hematuria since my PSA was so low and scan was negative. I did not fit the medical and insurance bellcurve for treatment. We are all our own best advocate.