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bob1955 avatar

ADT, maybe not? Anyone opted out of ADT?

Prostate Cancer | Last Active: 3 hours ago | Replies (83)

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@pesquallie

The Duke article opens with the statement: "Blocking testosterone production halts tumor growth in early disease, while elevating the hormone can delay disease progression in patients whose disease has advanced." If you are claiming, to someone who has just been diagnosed with early disease, that this research shows that "blocking testosterone production DOESN'T halt tumor growth", you are contradicting the Duke Health article. Perhaps I don't understand what you've written.

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Replies to "@pesquallie The Duke article opens with the statement: "Blocking testosterone production halts tumor growth in early..."

@climateguy
You need to be careful when reading the Duke report because they use the term hormone when speaking of testosterone which technically is a hormone. It is confusing but based on the quote below they are saying that high doses of testosterone are best for aggressive difficult to treat prostate cancer.

"In recent years, clinicians have begun treating patients with late-stage, therapy resistant prostate cancers using a monthly, high-dose injection of testosterone in a technique called bi-polar androgen therapy, or BAT. The inability to understand how this intervention works has hindered its widespread adoption as a mainstream therapeutic approach for prostate cancer patients.

For the whole article see: https://corporate.dukehealth.org/news/study-solves-testosterones-paradoxical-effects-prostate-cancer