Has anyone had success taking Alpha lipoic acid for neuropathy?

Posted by carol1024 @carol1024, Nov 18 8:22am

Has anyone had good results taking Alpha lipoic acid for neuropathy caused from Chemo (CIPN)? A fellow patient told me she didn't have neuropathy anymore and when I asked why, she said she was taking Alpha lipoic acid. I bought some and after getting approval from my oncologist, started taking 2 a day, the recommended dosage. When I did research to validate the benefits, some info was positive while some was indifferent. I honestly think it's working. It's been about 2 weeks. I will suggest if you do start using it, take it with a soda. I tried water, milk, after a meal and I had heartburn so bad. When I decided to take it with soda I had no heartburn at all. Dr Pepper works for me and I take it on an
empty stomach with my regular morning meds. I was just curious if someone had any positive feedback. Thanks

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Profile picture for carol1024 @carol1024

@njed I take 600mg but take twice a day. Could be that and the cream I ordered. I am having amazing results with that. I'm getting treatment now and have given info to several people. One is too big but you can Google Dermavitality and get all info. It's for oncology patients.

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@carol1024 Thanks for the info. So, what kind of results you are you experiencing. For example, less pain, less numbness? Ed

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Profile picture for NJ Ed @njed

@carol1024 Thanks for the info. So, what kind of results you are you experiencing. For example, less pain, less numbness? Ed

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@njed both

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Profile picture for darinjasman @darinjasman

@carol1024 if nerves are totally dead then how are you able to feel sensation still? Just curious.

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@darinjasman The sensation you feel is pain, numbness, and/or burning.

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Profile picture for mrmacabre @mrmacabre

@carol1024 All I know is that my levels of numbness and pain has increased over the past 10 years, and I'm not diabetic, not even close. I'm one of the lucky patients that went through every test there is to try and determine the root cause of my neuropathy, and was given a diagnosis of idiopathic poly neuropathy, no cause can be determined. So I have a hard time reading about people who's symptoms have been improved, if indeed they have been permanently.
My doctor, as well as all 4 neurologists that I saw over the course of almost 10 years have all said otherwise. It's permanent, in my case at least.

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@mrmacabre
I’ve had the same diagnosis as you; idiopathic neuropathy. The only thing the doctors figure could have caused it was the foot surgery I had years ago. I had decompression surgery and it didn’t work so I figure nothing will cure it. I use pain patches and creams. I’m very active so if I’m at a walking event I might take a tramadol for the pain. I find Motrin to work well when my toes swell but I mostly rely on pain patches. I’m not opposed to getting a spinal stimulator if the pain and discomfort interferes with my quality of life.

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Profile picture for bini41 @bini41

@mrmacabre
I’ve had the same diagnosis as you; idiopathic neuropathy. The only thing the doctors figure could have caused it was the foot surgery I had years ago. I had decompression surgery and it didn’t work so I figure nothing will cure it. I use pain patches and creams. I’m very active so if I’m at a walking event I might take a tramadol for the pain. I find Motrin to work well when my toes swell but I mostly rely on pain patches. I’m not opposed to getting a spinal stimulator if the pain and discomfort interferes with my quality of life.

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@bini41 mine is chemo induced peripheral neuropathy (CIPN) The doctors know what causes it. I have hydrocodone for my back and that comes in handy too. I have morphine ER15mg to take for the shot that self injects 27 hours after chemo. It's part of my immunotherapy that stimulates my bone marrow to produce white blood cells to help my immune system fight the cancer. The next 5 or 6 days are going to be very painful. I will be short of breath, have no energy at all and very weak, be in a lot of pain and be very off balance. I'll get through it though. I have 10 treatments so far but now it's that everything is coming faster. The side effects used to not start until about the 3 or 4 day after chemo. No they start the day or 2 after. After my treatment today on walk to the car my chest felt like it does when have been exercising or doing things to use chest muscles. It just felt tight.

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I am not sure, but I think it has slowed down, or even stopped, its progression.

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Profile picture for darinjasman @darinjasman

@carol1024 if nerves are totally dead then how are you able to feel sensation still? Just curious.

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@darinjasman

I was told by my neurologist that nerves can regenerate. Also, EMG tests are able to asccertain how much sensation/nerve damage there is. That is why they conduct that test. I never had any pain with PN--just some numbness, tingling and occasional ankle tightness; however, since going gluten free, my situation has improved. I am still taking B12 and ALA along with other vitamins. I also think our emotions can play a triggering role in PN. Stay curious--that is the pathway to more discoveries!

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There are studies on Alpha lipoic acid being somewhat helpful to people with diabetic PN. I have not found one single study for those of us with small fiber neuropathy, but I am taking the R-ALA anyway. No idea if it is working or not, though I have had less burning from the first 6 or 8 months when it started. It would be great if there was an actual study. There are so many studies on men's hair loss, but you know--that's important because it will make money.

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Profile picture for carol1024 @carol1024

@bini41 mine is chemo induced peripheral neuropathy (CIPN) The doctors know what causes it. I have hydrocodone for my back and that comes in handy too. I have morphine ER15mg to take for the shot that self injects 27 hours after chemo. It's part of my immunotherapy that stimulates my bone marrow to produce white blood cells to help my immune system fight the cancer. The next 5 or 6 days are going to be very painful. I will be short of breath, have no energy at all and very weak, be in a lot of pain and be very off balance. I'll get through it though. I have 10 treatments so far but now it's that everything is coming faster. The side effects used to not start until about the 3 or 4 day after chemo. No they start the day or 2 after. After my treatment today on walk to the car my chest felt like it does when have been exercising or doing things to use chest muscles. It just felt tight.

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@carol1024 I’m so sorry to hear this. I kinda know what you’re going through with your chemo because my brother had to have it three consecutive days every two weeks for a year. It must be difficult for you dealing with both chemo and your neuropathy. I will say a prayer for you.

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