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Completed 6 Pluvitco Injections. Oncologist moves me to Lynparza.
I've posted previously about moving from Taxotere to various spot/targeted radiations and finally on to Pluvitco. Pluvitco worked for a while and then stopped but even before completing the final injection, the oncologist, coordinating with the radiologist, prescribed Lynparza for me. If you've had this progression of treatments, can you provide an overview of your experience and what I may encounter on this journey. Many thanks in advance for all who can help me moving on.
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@jxj
I didn’t realize you completed your treatment. What did your scan show after.
@jeffmarc
Thank you
@jxj My radiologist and oncologist are in agreement that they will not do a scan until we're at least 4 weeks after the last Pluvicto treatment. Given the holidays, that means after the start of the new year. Frankly I have no idea what to expect.
Thanks for sharing. My husband will be starting on Pluvicto on Dec. 8th. Did you have any reactions to it?? Is it true you must stay away for 3 days ? Pets included ? The whole nuclear thing about it is just so scary to me. BTW my husband has Stage 4 Prostrate Cancer that has mestasasized. Thanks again
@ewatson201
You do need to keep that 6 foot distance. Pets included.
People go on Pluvicto when they have metastasis, Never heard of anyone getting it without them.
Some people have some major side effects from Pluvicto, most don’t. I have heard at least 5 people talk about their experience, In some cases they had to have more time between doses because of the side effects.
I saw a webinar where they discussed a person who lit up the Pet scan With metastasis from head to Legs. He had one Pluvicto Treatment and it almost cleared his pet scan, But his side effects were so bad that he could not take any more treatments
Be aware that it works really well for 33% of people OK for 33% of people and not at all for 33% of people.
If you have certain genetic issues, either hereditary or somatic, it can affect how well Pluvicto Works.
You can ask for a somatic test before doing Pluvicto To find out if you’ve got Genetic changes Due to the cancer.
If you have BRCA2 or ATM It seems to work better. If you have RB1, PTEN or TP53 They are Pluvicto resistant.
https://connect.mayoclinic.org/comment/1380711/
other comments about Pluvicto
I am 86 and will have my 4th Pluvicto infusion today.
I had 9 treatments of Chemo. The PSA started out at
86 and got down to 7. Chemo was a real bitch. Then after 11 months the PSA was back up to 80 and I started Pluvicto. My PSA has dropped like a rock. 80 to 40, then 40 to 13 and now 13 to 5.5.
My side effects have been minimum. Way better than chemo.
I am one of the lucky ones that Pluvicto works on!
My husband had six Pluvicto infusions over most of 2024 and had none of the severe side effects that some people experience. He had some fatigue, a dry mouth from his saliva glands being affected by the treatment, and his appetite for food decreased in that most things just didn't appeal to him. His last Pluvicto infusion was in August 2024, and the only side effect remaining is dry mouth.
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Thank you for responding. It is hard to find people who have had Pluvicto. He was diagnosed last Nov 1st and was only on meds till This past September when his PSA was 181 !!!!
He has had 10 rounds of radiation at the hospital and waiting for approval for Pluvicto treatment from our insurance. As of now it will be Dec 8th. My husband is 75, has A-FIB and has lost 100 pds since last year. He needed to thou, he was almost 294. The hardest part of this is I donlt know how long I will have him in my life. We have been married for 49 years, two beautiful daughters and have been best friends since 1978. I wish you nothing but health for a very very long time.
Ellen Watson
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